The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes.
RNA polymerase II may become arrested during transcript elongation, in which case the ternary complex remains intact but further RNA synthesis is blocked. To relieve arrest, the nascent transcript must be cleaved from the 3' end. RNAs of 7-17 nt are liberated and transcription continues from the new...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8058756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.17.8057 |
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