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The Valley of Death: Reciprocal sign epistasis constrains adaptive trajectories in a constant, nutrient limiting environment
The fitness landscape is a powerful metaphor for describing the relationship between genotype and phenotype for a population under selection. However, empirical data as to the topography of fitness landscapes are limited, owing to difficulties in measuring fitness for large numbers of genotypes unde...
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| Published in: | Genomics |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454348/ https://ncbi.nlm.nih.gov/pubmed/25449178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2014.10.011 |
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