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Generation of Mucosal Dendritic Cells from Bone Marrow Reveals a Critical Role of Retinoic Acid
It is unknown how dendritic cells (DCs) become specialized as mucosal DCs and maintain intestinal homeostasis. We report that bone marrow cells express the retinoic acid (RA)-synthesizing enzyme ALDH1a2, and provide RA to DC precursors in the bone marrow microenvironment. RA induced bone marrow-deri...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454342/ https://ncbi.nlm.nih.gov/pubmed/20944006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001233 |
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