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“Late sodium current: a mechanism for angina, heart failure, and arrhythmia”

The peak sodium current underlies excitability and conduction in heart muscle, but a late sodium current flowing after the peak contributes to maintaining and prolonging the action potential plateau, and also to intracellular sodium loading, that in turn increases intracellular calcium with conseque...

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Bibliographic Details
Published in:J Cardiovasc Pharmacol
Main Author: Makielski, Jonathan C.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454281/
https://ncbi.nlm.nih.gov/pubmed/19333133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181a1b9e7
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