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Engineering Cytochrome-Modified Silica Nanoparticles To Induce Programmed Cell Death

A low native membrane permeability and ineffective access to the cellular cytosol, together with aggressive proteolytic degradation, often severely hampers the practical application of any therapeutic protein or antibody. Through engineering the charging profile of mesoporous silica nanoparticles, c...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Huang, Wen-Yen, Davies, Gemma-Louise, Davis, Jason J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454278/
https://ncbi.nlm.nih.gov/pubmed/24249039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201303239
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