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Engineering Cytochrome-Modified Silica Nanoparticles To Induce Programmed Cell Death

A low native membrane permeability and ineffective access to the cellular cytosol, together with aggressive proteolytic degradation, often severely hampers the practical application of any therapeutic protein or antibody. Through engineering the charging profile of mesoporous silica nanoparticles, c...

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Détails bibliographiques
Publié dans:Chemistry
Auteurs principaux: Huang, Wen-Yen, Davies, Gemma-Louise, Davis, Jason J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454278/
https://ncbi.nlm.nih.gov/pubmed/24249039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201303239
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