Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder

A new multilayer-bead formulation of extended-release methylphenidate hydrochloride (MPH-MLR) has been evaluated in pharmacokinetic studies in healthy adults and in Phase III efficacy/safety studies in children and adolescents with attention deficit hyperactivity disorder (ADHD). Using available dat...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Teuscher, Nathan S, Adjei, Akwete, Findling, Robert L, Greenhill, Laurence L, Kupper, Robert J, Wigal, Sharon
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454220/
https://ncbi.nlm.nih.gov/pubmed/26060393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S83234
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