Gastrointestinal Stromal Tumors (GIST): A Prospective Analysis and an Update on Biomarkers and Current Treatment Concepts

Gastrointestinal stromal tumors (GIST) are the most common sarcomas of the gastrointestinal tract, with transformation typically driven by activating mutations of cKIT and less commonly platelet-derived growth factor receptor alpha (PDGFRA). Successful targeting of tyrosine-protein kinase Kit with i...

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Bibliographic Details
Published in:Biomark Cancer
Main Authors: Koumarianou, Anna, Economopoulou, Panagiota, Katsaounis, Panagiotis, Laschos, Konstantinos, Arapantoni-Dadioti, Petroula, Martikos, George, Rogdakis, Athanasios, Tzanakis, Nikolaos, Boukovinas, Ioannis
Format: Artigo
Language:Inglês
Published: Libertas Academica 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454203/
https://ncbi.nlm.nih.gov/pubmed/26056505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BIC.S25045
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