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Biased random walk model for the prioritization of drug resistance associated proteins

Multi-drug resistance is the main cause of treatment failure in cancer patients. How to identify molecules underlying drug resistance from multi-omics data remains a great challenge. Here, we introduce a data biased strategy, ProteinRank, to prioritize drug-resistance associated proteins in cancer c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Guo, Hao, Dong, Jiaqiang, Hu, Sijun, Cai, Xiqiang, Tang, Guangbo, Dou, Jianhua, Tian, Miaomiao, He, Fuchu, Nie, Yongzhan, Fan, Daiming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454201/
https://ncbi.nlm.nih.gov/pubmed/26039373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10857
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