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Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse
B-cell receptor (BCR) engagement with surface-tethered antigens leads to the formation of an immune synapse, which facilitates antigen uptake for presentation to T-lymphocytes. Antigen internalization and processing rely on the early dynein-dependent transport of BCR–antigen microclusters to the syn...
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| Yayımlandı: | Mol Biol Cell |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Cell Biology
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454175/ https://ncbi.nlm.nih.gov/pubmed/25631815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1373 |
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