Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction

Lung cancer represents the leading cause of cancer-related death in developed countries. Despite the advances in diagnostic and therapeutic techniques, the 5-year survival rate remains low. The research for novel therapies directed to biological targets has modified the therapeutic approach, but the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fortunato, O, Boeri, M, Moro, M, Verri, C, Mensah, M, Conte, D, Caleca, L, Roz, L, Pastorino, U, Sozzi, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454158/
https://ncbi.nlm.nih.gov/pubmed/25501825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.507
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