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Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?

A large variability in occurrence, complications, and age/gender manifestations characterizes individual susceptibility of sporadic thoracic aortic aneurysms (TAA), even in subjects with the same risk factor profiles. The reasons are poorly understood. On the other hand, TAA pathophysiology mechanis...

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Vydáno v:Age (Dordr)
Hlavní autoři: Balistreri, Carmela R., Pisano, Calogera, Martorana, Adriana, Triolo, Oreste F., Lio, Domenico, Candore, Giuseppina, Ruvolo, Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453932/
https://ncbi.nlm.nih.gov/pubmed/25129574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9700-x
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