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Crystal structure of caspase recruiting domain (CARD) of apoptosis repressor with CARD (ARC) and its implication in inhibition of apoptosis
Apoptosis repressor with caspase recruiting domain (ARC) is a multifunctional inhibitor of apoptosis that is unusually over-expressed or activated in various cancers and in the state of the pulmonary hypertension. Therefore, ARC might be an optimal target for therapeutic intervention. Human ARC is c...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Sci Rep |
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Prif Awduron: | , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Nature Publishing Group
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4453921/ https://ncbi.nlm.nih.gov/pubmed/26038885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09847 |
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