Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is among the most aggressive human malignancies with an overall 5-year survival rate of <5%. Despite significant advances in treatment of the disease during the past decade, the median survival rate (∼6 months) has hardly improved, warranting th...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Kaistha, B P, Honstein, T, Müller, V, Bielak, S, Sauer, M, Kreider, R, Fassan, M, Scarpa, A, Schmees, C, Volkmer, H, Gress, T M, Buchholz, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453723/
https://ncbi.nlm.nih.gov/pubmed/25137017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.460
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