Tumour-associated macrophages correlate with poor prognosis in myxoid liposarcoma and promote cell motility and invasion via the HB-EGF-EGFR-PI3K/Akt pathways

BACKGROUND: Myxoid liposarcoma (MLS) is the second most common subtype of liposarcoma, and metastasis occurs in up to one-third of cases. However, the mechanisms of invasion and metastasis remain unclear. Tumour-associated macrophages (TAMs) have important roles in tumour invasion, metastasis, and/o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Nabeshima, A, Matsumoto, Y, Fukushi, J, Iura, K, Matsunobu, T, Endo, M, Fujiwara, T, Iida, K, Fujiwara, Y, Hatano, M, Yokoyama, N, Fukushima, S, Oda, Y, Iwamoto, Y
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453656/
https://ncbi.nlm.nih.gov/pubmed/25562433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.637
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