Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in a subset of human epidermal growth factor receptor 2 (HER2)-positive breast cancers, and coexpression of HER2 and EGFR has been reported to be associated with poor clinical outcome. Moreover, interaction between HER2 and EGFR ha...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Lee, H J, Seo, A N, Kim, E J, Jang, M H, Kim, Y J, Kim, J H, Kim, S-W, Ryu, H S, Park, I A, Im, S-A, Gong, G, Jung, K H, Kim, H J, Park, S Y
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Translational Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453607/
https://ncbi.nlm.nih.gov/pubmed/25349977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.556
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