Fungal Inositol Pyrophosphate IP(7) Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity

Inositol pyrophosphates (PP-IPs) comprising inositol, phosphate, and pyrophosphate (PP) are essential for multiple functions in eukaryotes. Their role in fungal pathogens has never been addressed. Cryptococcus neoformans is a model pathogenic fungus causing life-threatening meningoencephalitis. We i...

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發表在:mBio
Main Authors: Lev, Sophie, Li, Cecilia, Desmarini, Desmarini, Saiardi, Adolfo, Fewings, Nicole L., Schibeci, Stephen D., Sharma, Raghwa, Sorrell, Tania C., Djordjevic, Julianne T.
格式: Artigo
語言:Inglês
出版: American Society of Microbiology 2015
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453010/
https://ncbi.nlm.nih.gov/pubmed/26037119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00531-15
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