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Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice

AIMS/HYPOTHESIS: Maternal obesity is associated with an increased risk of obesity and impaired glucose homeostasis in offspring. However, it is not known whether a gestational or pre-gestational exposure confers similar risks, and if so, what the underlying mechanisms are. METHODS: We used reciproca...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Sasson, Isaac E., Vitins, Alexa P., Mainigi, Monica A., Moley, Kelle H., Simmons, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452998/
https://ncbi.nlm.nih.gov/pubmed/25608625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3466-7
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