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The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism

Discussion on the role of DEHP in the critical period of gonadal development in pregnant rats (F0), studied the evolution of F1-F4 generation of inter-generational inheritance of cryptorchidism and the alteration of DNA methylation levels in testis. Pregnant SD rats were randomly divided into two gr...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Chen, Jinjun, Wu, Shengde, Wen, Sheng, Shen, Lianju, Peng, Jinpu, Yan, Chao, Cao, Xining, Zhou, Yue, Long, Chunlan, Lin, Tao, He, Dawei, Hua, Yi, Wei, Guanghui
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452760/
https://ncbi.nlm.nih.gov/pubmed/26035430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126403
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