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Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand

Maternal hypoxia is associated with a decrease in left ventricular capillary density while cardiac performance is preserved, implying a mismatch between metabolism and diffusive exchange. We hypothesised this requires a switch in substrate metabolism to maximise efficiency of ATP production from lim...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hauton, David, Al-Shammari, Abdullah, Gaffney, Eamonn A., Egginton, Stuart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452690/
https://ncbi.nlm.nih.gov/pubmed/26030353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127424
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