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Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells

In our previous study, we found that pretreatment with lipoamide (LM) more effectively than alpha-lipoic acid (LA) protected retinal pigment epithelial (RPE) cells from the acrolein-induced damage. However, the reasons and mechanisms for the greater effect of LM than LA are unclear. We hypothesize t...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhao, Lin, Liu, Zhongbo, Jia, Haiqun, Feng, Zhihui, Liu, Jiankang, Li, Xuesen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452644/
https://ncbi.nlm.nih.gov/pubmed/26030919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128502
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