Potential of (99m)Tc-MIBI SPECT imaging for evaluating non-alcoholic steatohepatitis induced by methionine-choline-deficient diet in mice

BACKGROUND: Hepatic mitochondrial dysfunction has been implicated in pathological conditions leading to non-alcoholic steatohepatitis (NASH). Technetium-99 m-2-methoxyisobutyl-isonitrile ((99m)Tc-MIBI), a lipophilic cationic myocardial perfusion agent, is retained in the mitochondria depending on me...

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Detalles Bibliográficos
Publicado en:EJNMMI Res
Autores principales: Rokugawa, Takemi, Uehara, Tomoya, Higaki, Yusuke, Matsushima, Shuuichi, Obata, Atsushi, Arano, Yasushi, Abe, Kohji
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452628/
https://ncbi.nlm.nih.gov/pubmed/26116119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0057-z
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