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The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos

Angiotensin-converting enzyme 2 (ACE2), its product Angiotensin-(1-7) [Ang-(1-7)], and Ang-(1-7) receptor Mas, have been shown to regulate organogenesis during embryonic development in various species. However, it is not known whether a local ACE2/Ang-(1-7)/Mas axis is present in the fetal pancreas....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Lin, Liang, Juan, Leung, Po Sing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452480/
https://ncbi.nlm.nih.gov/pubmed/26029927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128216
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