Treatment with Dimethyl Fumarate attenuates calcineurin inhibitor-induced Nephrotoxicity

BACKGROUND: Cyclosporine A (CsA) is an immunosuppressive drug which has been widely used to prevent rejection following organ transplantation. However, its therapeutic use is limited by nephrotoxicity, in part mediated by oxidative stress. The present study aims to investigate the protective effects...

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Veröffentlicht in:Transplantation
Hauptverfasser: Takasu, Chie, Vaziri, Nosratola D., Li, Shiri, Robles, Lourdes, Vo, Kelly, Takasu, Mizuki, Pham, Christine, Liu, Shuman, Farzaneh, Seyed H., Foster, Clarence E, Stamos, Michael J, Ichii, Hirohito
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452388/
https://ncbi.nlm.nih.gov/pubmed/25710612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000647
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