Identification of Novel Immune and Barrier Genes in Atopic Dermatitis by Laser Capture Micro-dissection

BACKGROUND: The molecular signature of atopic dermatitis/AD lesions is associated with Th2 and Th22 activation, and epidermal alterations. However, the epidermal and dermal AD transcriptomes and their respective contributions to abnormalities in respective immune and barrier phenotypes are unknown....

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Esaki, Hitokazu, Ewald, David A., Ungar, Benjamin, Rozenblit, Mariya, Zheng, Xiuzhong, Xu, Hui, Estrada, Yeriel D., Peng, Xiangyu, Mitsui, Hiroshi, Litman, Thomas, Suárez-Fariñas, Mayte, Krueger, James G., Guttman-Yassky, Emma
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452382/
https://ncbi.nlm.nih.gov/pubmed/25567045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.10.037
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