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Exploring Treatment by Covariate Interactions Using Subgroup Analysis and Meta-Regression in Cochrane Reviews: A Review of Recent Practice

BACKGROUND: Treatment by covariate interactions can be explored in reviews using interaction analyses (e.g., subgroup analysis). Such analyses can provide information on how the covariate modifies the treatment effect and is an important methodological approach for personalising medicine. Guidance e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Donegan, Sarah, Williams, Lisa, Dias, Sofia, Tudur-Smith, Catrin, Welton, Nicky
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452239/
https://ncbi.nlm.nih.gov/pubmed/26029923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128804
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