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Polymorphisms in Autophagy Genes Are Associated with Paget Disease of Bone
Paget disease of bone (PDB) is a focal bone disorder affecting the skeleton segmentally. The main alteration resides in osteoclasts that increase in size, number and activity. Many osteoclasts have cytoplasmic inclusions that have been associated with protein aggregates, increasing the evidences of...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452234/ https://ncbi.nlm.nih.gov/pubmed/26030385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128984 |
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