Polymorphisms in Autophagy Genes Are Associated with Paget Disease of Bone

Paget disease of bone (PDB) is a focal bone disorder affecting the skeleton segmentally. The main alteration resides in osteoclasts that increase in size, number and activity. Many osteoclasts have cytoplasmic inclusions that have been associated with protein aggregates, increasing the evidences of...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Usategui-Martín, Ricardo, García-Aparicio, Judith, Corral-Gudino, Luis, Calero-Paniagua, Ismael, Del Pino-Montes, Javier, González Sarmiento, Rogelio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452234/
https://ncbi.nlm.nih.gov/pubmed/26030385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128984
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