Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)

Autoantibody formation against Factor H (FH) is found in 7–10% of patients who are diagnosed with atypical haemolytic uraemic syndrome (aHUS). These autoantibodies predominately target the C-terminal cell binding recognition domain of FH and are associated with absence of FHR1. Additional autoantibo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Immunol
Main Authors: Watson, Rachael, Wearmouth, Emma, McLoughlin, Amy-Claire, Jackson, Arthur, Ward, Sophie, Bertram, Paula, Bennaceur, Karim, Barker, Catriona E., Pappworth, Isabel Y., Kavanagh, David, Lea, Susan M., Atkinson, John P., Goodship, Timothy H.J., Marchbank, Kevin J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452024/
https://ncbi.nlm.nih.gov/pubmed/25150608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.07.017
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