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Automatic signal extraction, prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS)

OBJECTIVE: Targeted drugs dramatically improve the treatment outcomes in cancer patients; however, these innovative drugs are often associated with unexpectedly high cardiovascular toxicity. Currently, cardiovascular safety represents both a challenging issue for drug developers, regulators, researc...

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Detalles Bibliográficos
Publicado en:J Biomed Inform
Main Authors: Xu, Rong, Wang, QuanQiu
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452013/
https://ncbi.nlm.nih.gov/pubmed/24177320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbi.2013.10.008
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