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Lack of Protection Against Ebola Virus from Chloroquine in Mice and Hamsters

The antimalarial drug chloroquine has been suggested as a treatment for Ebola virus infection. Chloroquine inhibited virus replication in vitro, but only at cytotoxic concentrations. In mouse and hamster models, treatment did not improve survival. Chloroquine is not a promising treatment for Ebola....

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Detalhes bibliográficos
Publicado no:Emerg Infect Dis
Main Authors: Falzarano, Darryl, Safronetz, David, Prescott, Joseph, Marzi, Andrea, Feldmann, Friederike, Feldmann, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451918/
https://ncbi.nlm.nih.gov/pubmed/25988934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2106.150176
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