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Sulforaphane attenuates EGFR signaling in NSCLC cells
BACKGROUND: EGFR, a receptor tyrosine kinase (RTK), is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC). Tyrosine kinase inhibitors (TKIs) have been widely used in the treatment of many cancers, including NSCLC. However, intrinsic and acquired resistance to TKI remains a co...
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Publicado no: | J Biomed Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451877/ https://ncbi.nlm.nih.gov/pubmed/26036303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0139-x |
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