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Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing

Pannexin1 (Panx1) is a gap junction gene in vertebrates whose proteins mainly function as non-junctional channels on the cell surface. Panx1 channels can release ATP under physiological conditions and play critical roles in many physiological and pathological processes. Here, we report that Panx1 de...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Jin, Zhu, Yan, Liang, Chun, Chen, Jing, Zhao, Hong-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451810/
https://ncbi.nlm.nih.gov/pubmed/26035172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10762
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