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A Novel Protein Interaction between Nucleotide Binding Domain of Hsp70 and p53 Motif

Currently, protein interaction of Homo sapiens nucleotide binding domain (NBD) of heat shock 70 kDa protein (PDB: 1HJO) with p53 motif remains to be elucidated. The NBD-p53 motif complex enhances the p53 stabilization, thereby increasing the tumor suppression activity in cancer treatment. Therefore,...

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Publicat a:Int J Genomics
Autors principals: Elengoe, Asita, Naser, Mohammed Abu, Hamdan, Salehhuddin
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451777/
https://ncbi.nlm.nih.gov/pubmed/26098630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/391293
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