Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin

The mechanism(s) by which fatty acids are sequestered and transported in muscle have not been fully elucidated. A potential key player in this process is the protein myoglobin (Mb). Indeed, there is a catalogue of empirical evidence supporting direct interaction of globins with fatty acid metabolite...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chintapalli, Sree V., Bhardwaj, Gaurav, Patel, Reema, Shah, Natasha, Patterson, Randen L., van Rossum, Damian B., Anishkin, Andriy, Adams, Sean H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451517/
https://ncbi.nlm.nih.gov/pubmed/26030763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128496
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