Pharmacobiological Approach for the Clinical Development of Ruxolitinib in Myeloproliferative Neoplasms

Ruxolitinib, a JAK1 and JAK2 inhibitor drug, has recently been approved for the treatment of patients with high- or intermediate-risk myelofibrosis with symptomatic splenomegaly. Ruxolitinib is the first clinically useful targeted therapy in Philadelphia chromosome-negative myeloproliferative neopla...

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Bibliografiske detaljer
Udgivet i:Turk J Haematol
Main Authors: Eliaçık, Eylem, Işık, Ayşe, Aksu, Salih, Üner, Ayşegül, Büyükaşık, Yahya, Sayınalp, Nilgün, Göker, Hakan, Özcebe, Osman İ., Haznedaroğlu, İbrahim C.
Format: Artigo
Sprog:Inglês
Udgivet: Galenos Publishing 2015
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451485/
https://ncbi.nlm.nih.gov/pubmed/26316485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2013.0265
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