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Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae

Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to ER-associated degradation, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited data exist des...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Buck, Teresa M., Jordan, Rick, Lyons-Weiler, James, Adelman, Joshua L., Needham, Patrick G., Kleyman, Thomas R., Brodsky, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451388/
https://ncbi.nlm.nih.gov/pubmed/25759377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00101.2014
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