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PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth

Kidney cancer [renal cell carcinoma (RCC)] is the sixth-most-common cancer in the United States, and its incidence is increasing. The current progression-free survival for patients with advanced RCC rarely extends beyond 1–2 yr due to the development of therapeutic resistance. We previously identifi...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Abu Aboud, Omran, Donohoe, Dallas, Bultman, Scott, Fitch, Mark, Riiff, Tim, Hellerstein, Marc, Weiss, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451352/
https://ncbi.nlm.nih.gov/pubmed/25810260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00322.2014
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