Disruption of Cholesterol 7α-Hydroxylase Gene in Mice: II. BILE ACID DEFICIENCY IS OVERCOME BY INDUCTION OF OXYSTEROL 7α-HYDROXYLASE

Past experiments and current paradigms of cholesterol homeostasis suggest that cholesterol 7α-hydroxylase plays a crucial role in sterol metabolism by controlling the conversion of cholesterol into bile acids. Consistent with this conclusion, we show in the accompanying paper that mice deficient in...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Schwarz, Margrit, Lund, Erik G., Setchell, Kenneth D. R., Kayden, Herbert J., Zerwekh, Joseph E., Björkhem, Ingemar, Herz, Joachim, Russell, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451191/
https://ncbi.nlm.nih.gov/pubmed/8663430
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