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Anti-Tumor Effects of Metformin in Animal Models of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

BACKGROUND: Several studies have reported that metformin can reduce the risk of hepatocellular carcinoma (HCC) in diabetes patients. However, the direct anti-HCC effects of metformin have hardly been studied in patients, but have been extensively investigated in animal models of HCC. We therefore pe...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Li, Juan, Hernanda, Pratika Y., Bramer, Wichor M., Peppelenbosch, Maikel P., van Luijk, Judith, Pan, Qiuwei
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451077/
https://ncbi.nlm.nih.gov/pubmed/26030161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127967
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