Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression.

Adoptive cellular immunotherapy, infusions of interleukin 2 (IL-2) in conjunction with in vitro-activated killer cells, has brought new hope to patients with cancer. The broad application of this strategy, however, is constrained by the need for repeated leukapheresis and by the labor-intensive proc...

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Main Authors:	Nakajima, F, Khanna, A, Xu, G, Lagman, M, Haschemeyer, R, Mouradian, J, Wang, J C, Stenzel, K H, Rubin, A L, Suthanthiran, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC44509/ https://ncbi.nlm.nih.gov/pubmed/8058730
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Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression.

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