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From Guide to Target: Molecular Insights into Eukaryotic RNAi Machinery

Since its relatively recent discovery, RNA interference (RNAi) has emerged as a potent, specific, and ubiquitous means of gene regulation. Through a number of pathways that are conserved from yeast to humans, small non-coding RNAs direct molecular machinery to silence gene expression. In this review...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Ipsaro, Jonathan J., Joshua-Tor, Leemor
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450863/
https://ncbi.nlm.nih.gov/pubmed/25565029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2931
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