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SLCO1B1 Polymorphism is not associated with Risk of Statin-Induced Myalgia/Myopathy in a Czech Population

BACKGROUND: Gene SLCO1B1, encoding solute organic anionic transport polypeptide OATP1B1, belongs to the group of candidates potentially influencing statin treatment safety. OATP1B1 regulates (not only) the hepatic uptake of statins. Its genetic variation was described as an important predictor of st...

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Publicat a:Med Sci Monit
Autors principals: Hubáček, Jaroslav A., Dlouhá, Dana, Adámková, Vera, Zlatohlávek, Lukáš, Viklický, Ondřej, Hrubá, Petra, Češka, Richard, Vrablík, Michal
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450600/
https://ncbi.nlm.nih.gov/pubmed/25992810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.893007
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