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The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patients

BACKGROUND: Oral tacrolimus therapy is effective for refractory ulcerative colitis (UC), but dose adjustment according to the trough concentrations which varies largely among individuals, is required. This study aimed to identify factors to predict the tacrolimus dose required for achieving the targ...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Hiraoka, Sakiko, Kato, Jun, Moritou, Yuki, Takei, Daisuke, Inokuchi, Toshihiro, Nakarai, Asuka, Takahashi, Sakuma, Harada, Keita, Okada, Hiroyuki, Yamamoto, Kazuhide
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450494/
https://ncbi.nlm.nih.gov/pubmed/25925267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0285-3
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