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Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging

With available MRI techniques, primary and metastatic liver cancers that are associated with high mortality rates and poor treatment responses are only diagnosed at late stages, due to the lack of highly sensitive contrast agents without Gd(3+) toxicity. We have developed a protein contrast agent (P...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Xue, Shenghui, Yang, Hua, Qiao, Jingjuan, Pu, Fan, Jiang, Jie, Hubbard, Kendra, Hekmatyar, Khan, Langley, Jason, Salarian, Mani, Long, Robert C., Bryant, Robert G., Hu, Xiaoping Philip, Grossniklaus, Hans E., Liu, Zhi-Ren, Yang, Jenny J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450423/
https://ncbi.nlm.nih.gov/pubmed/25971726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423021112
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