Effects of Intensive Diet and Exercise on Knee Joint Loads, Inflammation, and Clinical Outcomes Among Overweight and Obese Adults With Knee Osteoarthritis: The IDEA Randomized Clinical Trial

IMPORTANCE: Knee osteoarthritis (OA), a common cause of chronic pain and disability, has biomechanical and inflammatory origins and is exacerbated by obesity. OBJECTIVE: To determine whether a ≥10% reduction in body weight induced by diet, with or without exercise, would improve mechanistic and clin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JAMA
मुख्य लेखकों: Messier, Stephen P., Mihalko, Shannon L., Legault, Claudine, Miller, Gary D., Nicklas, Barbara J., DeVita, Paul, Beavers, Daniel P., Hunter, David J., Lyles, Mary F., Eckstein, Felix, Williamson, Jeff D., Carr, J. Jeffery, Guermazi, Ali, Loeser, Richard F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450354/
https://ncbi.nlm.nih.gov/pubmed/24065013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2013.277669
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