Development of an IP-Free Biotechnology Platform for Constitutive Production of HPV16 L1 Capsid Protein Using the Pichia pastoris PGK1 Promoter

The human papillomavirus (HPV) L1 major capsid protein, which forms the basis of the currently available vaccines against cervical cancer, self-assembles into virus-like particles (VLPs) when expressed heterologously. We report the development of a biotechnology platform for HPV16 L1 protein express...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Mariz, F. C., Coimbra, E. C., Jesus, A. L. S., Nascimento, L. M., Torres, F. A. G., Freitas, A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450287/
https://ncbi.nlm.nih.gov/pubmed/26090426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/594120
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