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Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity

Taxol triggers apoptosis in a variety of cancer cells, but it also upregulates cytoprotective proteins and/or pathways that compromise its therapeutic efficacy. In this report, we found that Taxol treatment resulted in caspase-8-dependent apoptosis in SKOV3 human ovarian cancer cells. Moreover, Taxo...

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Détails bibliographiques
Publié dans:Mol Cell Biochem
Auteurs principaux: Huang, Su, Day, Travis W., Choi, Mi-Ran, Safa, Ahmad R.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450256/
https://ncbi.nlm.nih.gov/pubmed/19415457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0147-9
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