Mannosylated Linear and Cyclic Single Amino Acid Mutant Peptides Using a Small 10 Amino Acid Linker Constitute Promising Candidates Against Multiple Sclerosis

Multiple sclerosis (MS) is a serious autoimmune demyelinating disease leading to loss of neurological function. The design and synthesis of various altered peptide ligands of immunodominant epitopes of myelin proteins to alter the autoimmune response, is a promising therapeutic approach for MS. In t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Day, Stephanie, Tselios, Theodore, Androutsou, Maria-Eleni, Tapeinou, Anthi, Frilligou, Irene, Stojanovska, Lily, Matsoukas, John, Apostolopoulos, Vasso
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450228/
https://ncbi.nlm.nih.gov/pubmed/26082772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00136
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