Essential Domains of Anaplasma phagocytophilum Invasins Utilized to Infect Mammalian Host Cells

Anaplasma phagocytophilum causes granulocytic anaplasmosis, an emerging disease of humans and domestic animals. The obligate intracellular bacterium uses its invasins OmpA, Asp14, and AipA to infect myeloid and non-phagocytic cells. Identifying the domains of these proteins that mediate binding and...

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Udgivet i:PLoS Pathog
Main Authors: Seidman, David, Hebert, Kathryn S., Truchan, Hilary K., Miller, Daniel P., Tegels, Brittney K., Marconi, Richard T., Carlyon, Jason A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450072/
https://ncbi.nlm.nih.gov/pubmed/25658707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004669
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