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Lymph-Node Resident CD8α(+) Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8(+) T Cell Responses

Malaria infection begins when a female Anopheles mosquito injects Plasmodium sporozoites into the skin of its host during blood feeding. Skin-deposited sporozoites may enter the bloodstream and infect the liver, reside and develop in the skin, or migrate to the draining lymph nodes (DLNs). Important...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Radtke, Andrea J., Kastenmüller, Wolfgang, Espinosa, Diego A., Gerner, Michael Y., Tse, Sze-Wah, Sinnis, Photini, Germain, Ronald N., Zavala, Fidel P., Cockburn, Ian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450069/
https://ncbi.nlm.nih.gov/pubmed/25658939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004637
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