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Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells

Genes or their encoded products are not expected to mingle with each other unless in some disease situations. In cancer, a frequent mechanism that can produce gene fusions is chromosomal rearrangement. However, recent discoveries of RNA trans-splicing and cis-splicing between adjacent genes (cis-SAG...

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Vydáno v:PLoS Genet
Hlavní autoři: Qin, Fujun, Song, Zhenguo, Babiceanu, Mihaela, Song, Yansu, Facemire, Loryn, Singh, Ritambhara, Adli, Mazhar, Li, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450057/
https://ncbi.nlm.nih.gov/pubmed/25658338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005001
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